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This is specially good for post-menopausal women as the lack ok estrogen can increase feminine pH. Rephresh is a good way to maintain a more acidic feminine pH in between topical dosages of prescription estradiol. Although prescription estradiol does lower feminine pH, the ph level never gets down to the normal low range seen in healthy reproductive women. A more acidic feminine pH is though to be consistent with a healthier profile of microbes, some of which also contribute to a more acidic pH. Using Rephresh augments the effect of using estradiol. pH decrease with Rephresh is temporary and mroe transient if used without prescription estradiol.